
Dr. Liu Nian
AWARD RECIPIENT

Benyuan Young PI Research Grant 2023

Tsinghua University

Using molecular, cellular, biochemical, high-throughput sequencing and biostatistics methods to study the mechanism of how transposon activity is regulated in the human genome
Introduction
He graduated from the Department of Polymer Materials and Engineering of the University of Science and Technology of China, and obtained his Ph.D. in Chemistry from the University of Chicago in 2015. He then completed postdoctoral research at Stanford University. In 2019, he was hired as a researcher at the School of Life Sciences and the Joint Center for Life Sciences of Tsinghua University.
His main research is to use molecular, cellular, biochemical, high-throughput sequencing and biostatistics to study the mechanism of how transposon activity is regulated in the human genome and its specific functions in development and disease.
Selected Publications
1.Hong Y*, Bie L*, Zhang T*, Yan X, Jin G, Chen Z, Wang Y, Li X, Pei G, Zhang Y, Hong Y, Gong L, Li P, Xie W, Zhu Y, Shen X, Liu N# (2024). SAFB restricts contact domain boundaries associated with L1 chimeric transcription. Molecular Cell, accepted.
2.Liu N*, Lee C*, Swigut T, Grow E, Gu B, Bassik M#, Wysocka J# (2018). Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators. Nature 553, 228-232.
3.Liu N, Dai Q, Zheng G, He C, Parisien M#, Pan T# (2015). N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions. Nature 518, 560-564.